Search results for "Asthma quality of life"

showing 2 items of 2 documents

SQ HDM SLIT-tablet (ALK) in treatment of asthma – Post hoc results from a randomised trial

2014

SummaryIntroductionIn a double-blind, placebo-controlled trial (EudraCT identifier: 2006-001795-20), the standardised quality (SQ) house dust mite (HDM) sublingual immunotherapy (SLIT)-tablet (ALK, Denmark) was investigated.MethodThe trial included 604 subjects, ≥14 years, with mild-moderate HDM allergic asthma. Subjects were randomised 1:1:1:1 to 1, 3 or 6 SQ-HDM or placebo once daily. The primary endpoint was reduction in inhaled corticosteroid (ICS) after one year. ICS reduction, asthma quality of life questionnaire (AQLQ) and asthma control questionnaire (ACQ) score was analysed post hoc in a subgroup with daily ICS use of 400–800 μg and ACQ score of 1–1.5, corresponding to partly contr…

AdultPulmonary and Respiratory MedicinePediatricsmedicine.medical_specialtymedicine.drug_classPopulationPlaceboHouse dust miteDouble-Blind MethodQuality of lifeSurveys and QuestionnairesmedicineClinical endpointAnimalsHumansSLIT-tabletBudesonideeducationGlucocorticoidsICS reductionAsthmaHouse dust miteSublingual Immunotherapyeducation.field_of_studybiologybusiness.industryPyroglyphidaemedicine.diseasebiology.organism_classificationAsthma; Asthma quality of life; House dust mite; ICS reduction; SLIT-tabletAsthmaTreatment OutcomeAsthma Control QuestionnaireQuality of LifeCorticosteroidAsthma quality of lifebusinessTabletsRespiratory Medicine
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Development of a nomogram to estimate the quality of life in asthmatic children using the Childhood Asthma Control Test

2016

Background: Pediatric Asthma Quality of Life Questionnaire (PAQLQ) provides detailed information on QoL in asthmatic children, whereas Childhood Asthma Control Test (C-ACT) Questionnaire is the most validated instrument for asthma control. No study assessed the relationship between C-ACT and QoL in children by means of those instruments. The aim of this study was to determine whether a QoL estimation is possible using the C-ACT questionnaire in asthmatic children. Methods: Medical history, spirometry, C-ACT, and PAQLQ were assessed in 144 (60% male) outpatient asthmatic children from September 2011 to November 2014. A generalized linear model (GLM) for the prediction of PAQLQ was obtained t…

SpirometryMalePediatricsmedicine.medical_specialtyPediatric Asthma Quality of Life QuestionnaireImmunologyPediatricsSeverity of Illness IndexChildhood Asthma Control Testnomogram03 medical and health sciencesFEV1/FVC ratio0302 clinical medicineQuality of lifechildren030225 pediatricsSurveys and QuestionnairesSeverity of illnessMedicineImmunology and AllergyHumansMedical historyPreschoolChildAsthmaChildhood asthmaasthma; Childhood Asthma Control Test; children; control; nomogram; Pediatric Asthma Quality of Life Questionnaire; Asthma; Child; Child Preschool; Female; Humans; Italy; Male; Pediatrics; Prognosis; Reproducibility of Results; Severity of Illness Index; Spirometry; Surveys and Questionnaires; Nomograms; Quality of Life; Pediatrics Perinatology and Child Health; Immunology and Allergy; Immunologymedicine.diagnostic_testbusiness.industryReproducibility of ResultsNomogramPerinatology and Child Healthasthmamedicine.diseasePrognosisNomograms030228 respiratory systemItalySpirometryChild PreschoolPediatrics Perinatology and Child HealthQuality of LifeFemaleasthma; Childhood Asthma Control Test; children; control; nomogram; Pediatric Asthma Quality of Life Questionnaire; Pediatrics Perinatology and Child Health; Immunology and Allergy; Immunologybusinesscontrol
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